Article
Association of serum interleukin-8 with virologic response to antiviral therapy in patients with chronic hepatitis C.
Journal of hepatology - 1 May 2004
Mihm Ulrike, Herrmann Eva, Sarrazin Ulrike, von Wagner Michael, Kronenberger Bernd, Zeuzem Stefan, Sarrazin Christoph
Abstract excerpt
BACKGROUND/AIMS: Upregulation of interleukin-8 by the hepatitis C virus non-structural-5A-protein leads to inhibition of the antiviral activity of interferon-alpha in vitro. The clinical significance of interleukin-8 levels for virologic response to interferon-alpha-based treatment in patients with chronic hepatitis C is unknown. METHODS: We investigated serum interleukin-8 in 59 healthy controls and 214 patients...
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