Article
Prevalence of mutations in hepatitis C virus core protein associated with alteration of NF-kappaB activation.
Virus research - 1 Oct 2006
Mann Elizabeth A, Stanford Sandra, Sherman Kenneth E
Abstract excerpt
The hepatitis C virus (HCV) core protein is a key structural element of the virion but also affects a number of cellular pathways, including nuclear factor kappaB (NF-kappaB) signaling. NF-kappaB is a transcription factor that regulates both anti-apoptotic and pro-inflammatory genes and its activ...
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