Article
Distinct functional role of Hepatitis C virus core protein on NF-kappaB regulation is linked to genomic variation.
Virus research - 1 Jul 2002
Ray Ratna B, Steele Robert, Basu Arnab, Meyer Keith, Majumder Mainak, Ghosh Asish K, Ray Ranjit
Abstract excerpt
Hepatitis C virus (HCV) often causes a prolonged and persistent infection. Sequence divergence in the HCV genome indicates several genotypes and a series of subtypes for this virus. The core protein of HCV has many intriguing functional properties and is implicated as a factor in virus mediated pathogenesis. Nuclear factor kappaB (NF-kappaB), a transcription factor, responds to inflammatory signals, activates the...
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