Article
Associations of variations in alcohol dehydrogenase genes with the level of response to alcohol in non-Asians.
Alcoholism, clinical and experimental research - 1 Sept 2006
Duranceaux Nicole C E, Schuckit Marc A, Eng Mimy Y, Robinson Shannon K, Carr Lucinda G, Wall Tamara L
Abstract excerpt
BACKGROUND: Risk and protective factors for alcohol use disorders (AUDs) are complex and reflect both environmental and genetic factors. Genetic components account for about 50% of the variation and influence several phenotypes, including the level of response (LR) to alcohol as well as alcohol-metabolizing enzyme polymorphisms. Variations in the ADH1B and ADH1C genes may influence the LR to alcohol by increasing...
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