Article
ALDH2 and ADH1B interactions in retrospective reports of low-dose reactions and initial sensitivity to alcohol in Asian American college students.
Alcoholism, clinical and experimental research - 1 Jul 2011
Luczak Susan E, Pandika Danielle, Shea Shoshana H, Eng Mimy Y, Liang Tiebing, Wall Tamara L
Abstract excerpt
BACKGROUND: A mechanistic model has been proposed for how alcohol-metabolizing gene variants protect individuals from the development of alcohol use disorders, with heightened sensitivity to alcohol being an early step (endophenotype) in this model. This study was designed to determine whether possession of 2 alcohol-metabolizing genes variations, the aldehyde dehydrogenase ALDH2*2 allele and the alcohol...
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