Article
Statistical analysis of antigen receptor spectratype data.
Bioinformatics (Oxford, England) - 15 Aug 2005
Kepler Thomas B, He Min, Tomfohr John K, Devlin Blythe H, Sarzotti Marcella, Markert M Louise
Abstract excerpt
MOTIVATION: The effectiveness of vertebrate adaptive immunity depends crucially on the establishment and maintenance of extreme diversity in the antigen receptor repertoire. Spectratype analysis is a method used in clinical and basic immunological settings in which antigen receptor length diversity is assessed as a surrogate for functional diversity. The purpose of this paper is to describe the systematic...
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