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Article

Evolution of antifungal-drug resistance: mechanisms and pathogen fitness.

Nature reviews. Microbiology - 1 Jul 2005

Anderson James B

Abstract excerpt

Like other microorganisms, fungi exist in populations that are adaptable. Under the selection imposed by antifungal drugs, drug-sensitive fungal pathogens frequently evolve resistance. Although the molecular mechanisms of resistance are well-characterized, there are few measurements of the impact of these mechanisms on pathogen fitness in different environments. To predict resistance before a new drug is...

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PMID: 15953931
DOI: 10.1038/nrmicro1179

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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