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Article

A three‐dimensional <i>in vitro</i> model system to study the adaptation of craniofacial skeletal muscle following mechanostimulation

1 Jun 2005

Abstract excerpt

The aim of this study was to investigate the in vitro response of human craniofacial muscle-derived myotubes (primitive/nascent muscle fibres), in three-dimensional constructs, to strain in vitro to mimic clinical scenarios, using expression of the mechanoresponsive gene gelatinase-A/matrix metalloproteinase-2 (MMP-2) as a marker of remodelling of muscle extracellular matrix. Three-dimensional (3D) constructs of...

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PMID: 15953246
DOI: 10.1111/j.1600-0722.2005.00215.x

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