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Article

Ex vivo expansion of limbal stem cells is affected by substrate properties.

Stem cell research - 1 May 2012

Jones Roanne R, Hamley Ian W, Connon Che J

Abstract excerpt

Limbal epithelial stem cells play a key role in the maintenance and regulation of the corneal surface. Damage or destruction of these cells results in vascularisation and corneal opacity. Subsequent limbal stem cell transplantation requires an ex vivo expansion step and preserving cells in an undifferentiated state remains vital. In this report we seek to control the phenotype of limbal epithelial stem cells by...

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Identifiers

PMID: 22386779
DOI: 10.1016/j.scr.2012.01.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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