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Article

Mechanostimulation changes the catabolic phenotype of human dedifferentiated osteoarthritic chondrocytes.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA - 1 Jan 2015

Halbwirth Florian, Niculescu-Morzsa Eugenia, Zwickl Hannes, Bauer Christoph, Nehrer Stefan

Abstract excerpt

PURPOSE: The treatment of cartilage defects with matrix-embedded autologous chondrocytes is a promising method to support the repair process and to foster reconstitution of full functionality of the joint. METHODS: Human osteoarthritic chondrocytes were harvest from nine different patients (mean ± SD age 68 ± 8 years) who underwent total knee replacement. The chondrocytes were embedded after a precultivation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25377190
DOI: 10.1007/s00167-014-3412-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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