Article
Mechanical force modulates scleraxis expression in bioartificial tendons.
Journal of musculoskeletal & neuronal interactions - 1 Jun 2011
Scott A, Danielson P, Abraham T, Fong G, Sampaio A V, Underhill T M
Abstract excerpt
Following tendon injury, cartilage, bone and fat metaplasia are often observed, making the optimization of tenocyte differentiation an important clinical goal. In this study we examined the effect of static and cyclic mechanical loading on the expression of genes which play a role in tenocyte differentiation and function, namely scleraxis (Scx) and Type I collagen (Col1a1), and determined the effect of varying...
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