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Article

Development of a three-dimensional in vitro model system to study orthodontic tooth movement.

Archives of oral biology - 1 Oct 2013

Heckler A F, Mirzaei Z, Pereira I, Simmons C A, Gong S-G

Abstract excerpt

Few three-dimensional (3-D) models exist to study the cellular aspects and molecular regulation of orthodontic tooth movement (OTM). The aim of this study was to develop a 3-D in vitro model to study mechanical loading of human periodontal ligament (PDL) fibroblasts (hPDLF). hPDLF were seeded within collagen gels to form a PDLF analogue. Characterisation of the seeded collagen gels revealed that the gels...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23845751
DOI: 10.1016/j.archoralbio.2013.06.011

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