Article
A comparison of the ability of intra-oral and extra-oral fibroblasts to stimulate extracellular matrix reorganization in a model of wound contraction.
Journal of dental research - 1 Jun 1996
Stephens P, Davies K J, al-Khateeb T, Shepherd J P, Thomas D W
Abstract excerpt
Intra-oral wounds, like wounds in children, demonstrate privileged healing when compared with adult wounds at extra-oral sites. This study investigated whether this preferential healing is related to an increased ability of oral mucosal fibroblasts to reorganize extracellular matrix (ECM) when compared with their dermal counterparts. ECM reorganization was investigated by means of a fibroblast-populated collagen...
Topics
- Adolescent
- Adult
- Age Factors
- Cell Adhesion
- Cells, Cultured
- Child
- Collagen
- Contractile Proteins
- Culture Media, Conditioned
- Extracellular Matrix
- Fibroblasts
- Humans
- Mouth Mucosa
- Phenotype
- Skin