Article
The clinical significance of viral fitness.
Journal of HIV therapy - 1 Mar 2005
Geretti Anna Maria
Abstract excerpt
Increasing evidence indicates that antiretroviral drug resistance is associated with impaired viral fitness and that this impairment can translate, at least transiently, into a virological and immunological benefit. The optimal strategies for exploiting the fitness cost associated with drug resistance remain to be determined. For highly drug-experienced patients receiving salvage therapy with a detectable viral...
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