Article
Virus fitness: concept, quantification, and application to HIV population dynamics.
Current topics in microbiology and immunology - 1 Jan 2006
Quiñones-Mateu M E, Arts E J
Abstract excerpt
Viral fitness has been broadly studied during the past three decades, mainly to test evolutionary models and population theories difficult to analyze and interpret with more complex organisms. More recent studies, however, are focused in the role of fitness on viral transmission, pathogenesis, and drug resistance. Here, we used human immunodeficiency virus (HIV) as one of the most relevant models to evaluate the...
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