Article
Practical applications of viral fitness in clinical practice.
Current opinion in infectious diseases - 1 Feb 2003
Bates Michael, Wrin Terri, Huang Wei, Petropoulos Christos, Hellmann Nicholas
Abstract excerpt
PURPOSE OF REVIEW: To review recent clinical data regarding viral fitness and its potential utility in clinical practice. Therapeutic failure of antiretroviral regimens is often due to the development of drug resistance. The viral loads achieved by these drug-resistant variants frequently remain suppressed below pretreatment levels. Furthermore, many patients with virologic failure continue to maintain stable CD4...
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