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Article

CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency.

The Journal of biological chemistry - 19 Aug 2005

Grunkemeyer James A, Kwoh Christopher, Huber Tobias B, Shaw Andrey S

Abstract excerpt

Mice born without CD2-associated protein (CD2AP) develop renal failure and nephrotic syndrome about 4 weeks after birth and die around 6 weeks of age. Although CD2AP is widely expressed, the severity of the renal failure precludes a clear determination of the role of CD2AP in other tissues. Here we generated transgenic mice expressing CD2AP using a podocyte-specific promoter. Podocyte-specific expression of CD2AP...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15951437
DOI: 10.1074/jbc.M504004200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency.PMID 15951437Read ↗

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