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Article

CD2AP and p130Cas localize to different F-actin structures in podocytes

1 Oct 2001

Abstract excerpt

Mice lacking the 80-kDa CD2-associated protein (CD2AP) develop progressive renal failure that starts soon after birth with proteinuria and foot process effacement by unknown mechanisms. CD2AP has been identified and cloned independently by virtue of its interaction with the T cell protein CD2 and with the docking protein p130Cas. In the present study we examined the localization of CD2AP and p130Cas in the mouse...

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Identifiers

PMID: 11553524
DOI: 10.1152/ajprenal.2001.281.4.f769

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CD2AP and p130Cas localize to different F-actin structures in podocytesPMID 11553524Read ↗

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