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Article

Evidence of an adaptive response targeting DNA nonhomologous end joining and its transmission to bystander cells.

Cancer research - 1 Nov 2010

Klammer Holger, Kadhim Munira, Iliakis George

Abstract excerpt

Adaptive response (AR) is a term describing resistance to ionizing radiation-induced killing or formation of aberrant chromosomes that is mediated by pre-exposure to low ionizing radiation doses. The mechanism of AR remains elusive. Because cell killing and chromosome aberration formation derive from erroneous processing of DNA double-strand breaks (DSB), AR may reflect a modulation of DSB processing by...

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PMID: 20861183
DOI: 10.1158/0008-5472.CAN-10-1181

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ATM
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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