Article
p53 codon 72 polymorphism association with head and neck squamous cell carcinoma.
Brazilian journal of otorhinolaryngology - 1 Jan 2000
Mojtahedi Zahra, Hashemi Seyed Basir, Khademi Bijan, Karimi Morteza, Haghshenas Mohammad Reza, Fattahi Mohammad Javad, Ghaderi Abbas
Abstract excerpt
UNLABELLED: p53 tumoral suppressor gene harbors a functional polymorphism which codes either arginine (Arg) or proline (Pro) in the protein p53 of codon 72. Such polymorphism has been associated with the development or prognosis of head and neck squamous cell carcinoma (HNSCC). AIM: we assessed codon 72 p53 allelic frequencies and genotypes in HNSCC Iranian patients. STUDY DESIGN: Case Study. MATERIALS AND...
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