Article
Effects of HRAS oncogene on cell cycle progression in a cervical cancer-derived cell line.
Archives of medical research - 1 Jan 2000
Córdova-Alarcón Emilio, Centeno Federico, Reyes-Esparza Jorge, García-Carrancá Alejandro, Garrido Efraín
Abstract excerpt
BACKGROUND: Human papillomavirus (HPV) infection is the most prevalent factor in anogenital cancers. However, epidemiological surveys and molecular data indicate that viral presence is not enough to induce cervical cancer, suggesting that cellular factors could play a key role. One of the most important genes involved in cancer development is the RAS oncogene, and activating mutations in this gene have been...
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