Article
CDC42 Gtpase Activation Affects Hela Cell DNA Repair and Proliferation Following UV Radiation-Induced Genotoxic Stress.
Journal of cellular biochemistry - 1 Sept 2015
Ascer Liv G, Magalhaes Yuli T, Espinha Gisele, Osaki Juliana H, Souza Renan C, Forti Fabio L
Abstract excerpt
Cell division control protein 42 (CDC42) homolog is a small Rho GTPase enzyme that participates in such processes as cell cycle progression, migration, polarity, adhesion, and transcription. Recent studies suggest that CDC42 is a potent tumor suppressor in different tissues and is related to aging processes. Although DNA damage is crucial in aging, a potential role for CDC42 in genotoxic stress remains to be...
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