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The Cell Cycle Timing of Human Papillomavirus DNA Replication

1 Jul 2015

Abstract excerpt

Viruses manipulate the cell cycle of the host cell to optimize conditions for more efficient viral genome replication. One strategy utilized by DNA viruses is to replicate their genomes non-concurrently with the host genome; in this case, the viral genome is amplified outside S phase. This phenomenon has also been described for human papillomavirus (HPV) vegetative genome replication, which occurs in G2-arrested...

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PMID: 26132923
DOI: 10.1371/journal.pone.0131675

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