Article
BRAF mutation detection and identification by cycling temperature capillary electrophoresis.
Electrophoresis - 1 Jun 2005
Hinselwood David C, Abrahamsen Torveig W, Ekstrøm Per O
Abstract excerpt
BRAF mutations are found in many human tumors, namely melanomas ( approximately 70%) and colon carcinomas ( approximately 15%). This paper presents a method for identification of exon 15 BRAF mutations by denaturant capillary electrophoresis (CE), an analysis method that is sensitive, cost-effective (involving only polymerase chain reaction (PCR) and electrophoresis) and capable of high-throughput screening. In...
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