Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRAF mutations are detectable in conjunctival but not uveal melanomas.

Melanoma research - 1 Dec 2004

Spendlove Hayley E, Damato Bertil E, Humphreys Jane, Barker Karen T, Hiscott Paul S, Houlston Richard S

Abstract excerpt

Activating mutations in exon 15 of BRAF have been detected in a high proportion of cutaneous melanomas. To determine whether such mutations are a feature of conjunctival or uveal melanomas, we screened DNA from these tumours. Twenty-one conjunctival and 88 uveal tumours were included in the study. Mutation analysis of BRAF exons 11 and 15 was undertaken using a combination of conformationally sensitive gel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conjunctival Neoplasms
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Melanoma

Share to Proto-Oncogene Proteins B-raf

Share to Skin Neoplasms

Share to Tumor Cells, Cultured

Share to Uveal Neoplasms

Source

Identifiers

PMID: 15577314
DOI: 10.1097/00008390-200412000-00003

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRAF mutations are detectable in conjunctival but not uveal melanomas.PMID 15577314Read ↗

BRAF mutations in conjunctival melanoma.Semantic proximity Read ↗

Absence of BRAF and NRAS mutations in uveal melanoma.Semantic proximity Read ↗

Absence of BRAF gene mutations in uveal melanomas in contrast to cutaneous melanomas.Semantic proximity Read ↗

Prevalence of exon 15 BRAF mutations in primary melanoma of the superficial spreading, nodular, acral, and lentigo maligna subtypes.Semantic proximity Read ↗

Exon 15 BRAF mutations are uncommon in canine oral malignant melanomas.Semantic proximity Read ↗

B-raf exon 15 mutations are common in primary melanoma resection specimens but not associated with clinical outcome.Semantic proximity Read ↗

Cutaneous melanoma subtypes show different BRAF and NRAS mutation frequencies.Semantic proximity Read ↗

Analysis of BRAF and N-RAS mutations in metastatic melanoma tissues.Semantic proximity Read ↗

The oncogenic B-raf V599E mutation occurs more frequently in melanomas at sun-protected body sites.Semantic proximity Read ↗

The T1799A<i>BRAF</i>Mutation Is Present in Iris MelanomaSemantic proximity Read ↗

Response to targeted therapy in two patients with metastatic melanoma carrying rare BRAF exon 15 mutations: A598_T599insV and V600_K601delinsE.Semantic proximity Read ↗

Contribution of Germline Mutations in<i>BRCA2</i>,<i>P16<sup><i>INK4A</i></sup></i>,<i>P14<sup><i>ARF</i></sup></i>and<i>P15</i>to Uveal MelanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.