Exploring Taq polymerase induced mutations in part of BRAF exon 15 by sequencing and mutation enrichment.

Abstract excerpt

The polymerase chain reaction (PCR) is a fundamental technique in molecular biology, enabling the amplification of specific DNA sequences for various applications. Despite its utility, the fidelity of DNA polymerases used during amplification is not perfect, leading to the introduction of replication errors such as base substitutions, insertions, and deletions into the amplified products. These errors can...

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