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Article

Altered nucleosome occupancy and histone H3K4 methylation in response to 'transcriptional stress'.

The EMBO journal - 6 Jul 2005

Zhang Lian, Schroeder Stephanie, Fong Nova, Bentley David L

Abstract excerpt

We report that under 'transcriptional stress' in budding yeast, when most pol II activity is acutely inhibited, rapid deposition of nucleosomes occurs within genes, particularly at 3' positions. Whereas histone H3K4 trimethylation normally marks 5' ends of highly transcribed genes, under 'transcriptional stress' induced by 6-azauracil (6-AU) and inactivation of pol II, TFIIE or CTD kinases Kin28 and Ctk1, this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15944735
DOI: 10.1038/sj.emboj.7600711
PMCID: PMC1173152

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Source receipt: pubmed, retrieved 7 Sept 2026.

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