Article
Evolution of the tandem repeats in thymidylate synthase enhancer region (TSER) in primates.
Gene - 18 Aug 2004
Zhang Yun-Wu, Luo Huai-Rong, Ryder Oliver A, Zhang Ya-Ping
Abstract excerpt
The upstream regulatory region of the human thymidylate synthase gene (thymidylate synthase enhancer region, TSER) is length polymorphic, attributable to variable numbers of tandemly repeated copies of a 28-bp fragment. It has been found that TSER length polymorphism is correlated to malignancy risk. To further our understanding of the origin and evolution of TSER, this region was investigated among different...
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