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Article

Interaction of the Ty3 reverse transcriptase thumb subdomain with template-primer.

The Journal of biological chemistry - 26 Aug 2005

Bibillo Arkadiusz, Lener Daniela, Tewari Alok, Le Grice Stuart F J

Abstract excerpt

Amino acid sequence alignment was used to identify the putative thumb subdomain of reverse transcriptase (RT) from the Saccharomyces cerevisiae long terminal repeat-containing retrotransposon Ty3. The counterpart to helix alphaH of human immunodeficiency virus type 1 (HIV-1) RT, which mediates important interactions with a duplex nucleic acid approximately 3-6 bp behind the DNA polymerase catalytic center, was...

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PMID: 15944162
DOI: 10.1074/jbc.M502457200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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