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Article

APOBEC3G targets human T-cell leukemia virus type 1.

Retrovirology - 19 May 2005

Sasada Amane, Takaori-Kondo Akifumi, Shirakawa Kotaro, Kobayashi Masayuki, Abudu Aierkin, Hishizawa Masakatsu, Imada Kazunori, Tanaka Yuetsu, Uchiyama Takashi

Abstract excerpt

BACKGROUND: Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is a host cellular protein with a broad antiviral activity. It inhibits infectivitiy of a wide variety of retroviruses by deaminating deoxycytidine (dC) into deoxyuridine (dU) in newly synthesized minus strand DNA, resulting in G-to-A hypermutation of the viral plus strand DNA. To clarify the mechanism of its function, we...

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Identifiers

PMID: 15943885
DOI: 10.1186/1742-4690-2-32
PMCID: PMC1156950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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