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Article

[Mechanisms for inhibition of retrovirus replication by APOBEC3 family].

Uirusu - 1 Jun 2011

Iwatani Yasumasa

Abstract excerpt

Human cells developed the defense systems against retrovirus infections during the evolutions. These systems include retroviral restrictions by DNA cytidine deaminases of APOBEC3 family (A, B, C, DE, F, G, and H), which are potent factors to block the viral replication by blocking reverse transcription and/or integration and by hypermutating viral cDNA. In case of HIV-1, the viral protein, Vif abrogates the...

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Source

Identifiers

PMID: 21972557
DOI: 10.2222/jsv.61.67

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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