Article
Deletion mapping of chromosomes 14q and 1p in human neuroblastoma.
Oncogene - 1 Jun 1992
Takayama H, Suzuki T, Mugishima H, Fujisawa T, Ookuni M, Schwab M, Gehring M, Nakamura Y, Sugimura T, Terada M
Abstract excerpt
It has been suggested that loss of heterozygosity (LOH) on the short arm of chromosome 1 is a critical event for the development of neuroblastoma, and we have previously shown frequent LOH on chromosome 14 in neuroblastoma. To pursue these observations, especially to define further the regions wh...
Topics
- Alleles
- Blotting, Southern
- Brain Neoplasms
- Child
- Child, Preschool
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 14
- DNA Probes
- DNA, Neoplasm
- Genotype
- Heterozygote
- Humans
- Infant
- Neoplasm Staging
- Neuroblastoma