Article
Loss of heterozygosity for alleles on chromosomes 11q and 14q in neuroblastoma.
Progress in clinical and biological research - 1 Jan 1991
Srivatsan E S, Murali V, Seeger R C
Abstract excerpt
Partial monosomy for the short arm of chromosome 1 is a frequent cytogenetic abnormality in neuroblastomas. Molecular genetic analysis of tumor samples using chromosome specific polymorphic DNA markers has identified somatic loss of heterozygosity for alleles on chromosomes 1p (1p36.1-1p36.3) and 14q. In order to determine if other chromosomal losses occur and to further investigate chromosome 14, we used...
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