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Article

Loss of heterozygosity for alleles on chromosomes 11q and 14q in neuroblastoma.

Progress in clinical and biological research - 1 Jan 1991

Srivatsan E S, Murali V, Seeger R C

Abstract excerpt

Partial monosomy for the short arm of chromosome 1 is a frequent cytogenetic abnormality in neuroblastomas. Molecular genetic analysis of tumor samples using chromosome specific polymorphic DNA markers has identified somatic loss of heterozygosity for alleles on chromosomes 1p (1p36.1-1p36.3) and 14q. In order to determine if other chromosomal losses occur and to further investigate chromosome 14, we used...

Topics

Alleles
Bone Marrow
Bone Marrow Cells
Chromosome Aberrations
Chromosome Disorders
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 14
Cloning, Molecular
DNA, Neoplasm
Heterozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuroblastoma

Nucleic Acid Hybridization

Plasmids

Source

Identifiers

PMID: 2068183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2068183-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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