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Article

Deletion mapping of 14q32 in human neuroblastoma defines an 1,100-kb region of common allelic loss.

Medical and pediatric oncology - 1 Dec 2000

Hoshi M, Shiwaku H O, Hayashi Y, Kaneko Y, Horii A

Abstract excerpt

BACKGROUND: We analyzed loss of heterozygosity (LOH) in 54 primary neuroblastomas (NBs) using 12 microsatellite markers on 14q32, and found that 31% (17/54) NBs showed LOH. PROCEDURE: The smallest region of overlap (SRO) was identified between D14S62 and D14S987. RESULTS: There was no statistical correlation between LOH and any clinicopathologic features, including age, stage, amplification of MYCN, and ploidy. A...

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Source

Identifiers

PMID: 11107107
DOI: 10.1002/1096-911x(20001201)35:6<522::aid-mpo4>3.0.co;2-6

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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