Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss.

British journal of cancer - 1 Jun 2000

Hoshi M, Otagiri N, Shiwaku H O, Asakawa S, Shimizu N, Kaneko Y, Ohi R, Hayashi Y, Horii A

Abstract excerpt

Neuroblastoma (NB) is a well-known malignant disease in infants, but its molecular mechanisms have not yet been fully elucidated. To investigate the genetic contribution of abnormalities on the long arm of chromosome 14 (14q) in NB, we analysed loss of heterozygosity (LOH) in 54 primary NB samples using 12 microsatellite markers on 14q32. Seventeen (31%) of 54 tumours showed LOH at one or more of the markers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 14
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, myc

Share to Genes, Tumor Suppressor

Share to In Situ Hybridization, Fluorescence

Share to Loss of Heterozygosity

Share to Neuroblastoma

Share to Ploidies

Source

Open in PubMed Open full text

Identifiers

PMID: 10839294
DOI: 10.1054/bjoc.2000.1108
PMCID: PMC2363232

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss.PMID 10839294Read ↗

Deletion mapping of 14q32 in human neuroblastoma defines an 1,100-kb region of common allelic loss.Semantic proximity Read ↗

Loss of heterozygosity for chromosome 14q in neuroblastomaSemantic proximity Read ↗

Deletion mapping of chromosomes 14q and 1p in human neuroblastoma.Semantic proximity Read ↗

Smallest region of overlapping deletion in 1p36 in human neuroblastoma: A 1 Mbp cosmid and PAC contigSemantic proximity Read ↗

Allelic deletion at chromosome bands 11q14-23 is common in neuroblastoma.Semantic proximity Read ↗

Delineation of the frequency and boundary of chromosomal copy number variations in paediatric neuroblastomaSemantic proximity Read ↗

Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma.Semantic proximity Read ↗

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas.Semantic proximity Read ↗

Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.Semantic proximity Read ↗

Identification of candidate genes involved in neuroblastoma progression by combining genomic and expression microarrays with survival data.Semantic proximity Read ↗

Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.Semantic proximity Read ↗

Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.