Article
CTCF Regulates Growth and Erythroid Differentiation of Human Myeloid Leukemia Cells
8 Jun 2005
Abstract excerpt
CTCF is a transcription factor and a candidate tumor suppressor that contains a DNA-binding domain composed of 11 zinc fingers. We reported previously that CTCF is differentially regulated during differentiation of human myeloid leukemia cells. In this study we aimed to investigate the role of CTCF in myeloid cell differentiation. A human cell line, K562, that can be chemically induced to differentiate into...
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