Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA-binding factor Ctcf critically controls gene expression in macrophages.

Cellular & molecular immunology - 1 Jan 2014

Nikolic Tatjana, Movita Dowty, Lambers Margaretha E H, Ribeiro de Almeida Claudia, Biesta Paula, Kreefft Kim, de Bruijn Marjolein J W, Bergen Ingrid, Galjart Niels, Boonstra Andre, Hendriks Rudi

Abstract excerpt

Macrophages play an important role in immunity and homeostasis. Upon pathogen recognition via specific receptors, they rapidly induce inflammatory responses. This process is tightly controlled at the transcriptional level. The DNA binding zinc-finger protein CCCTC-binding factor (Ctcf) is a crucial regulator of long-range chromatin interactions and coordinates specific communication between transcription factors...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCCTC-Binding Factor
Share to Immunoenzyme Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Integrases

Share to Lipopolysaccharides

Share to Major Histocompatibility Complex

Share to Myeloid Cells

Share to Phagocytosis

Share to Toll-Like Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 24013844
DOI: 10.1038/cmi.2013.41
PMCID: PMC4002140

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA-binding factor Ctcf critically controls gene expression in macrophages.PMID 24013844Read ↗

TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophagesSemantic proximity Read ↗

Cxxc Finger Protein 1 Positively Regulates GM-CSF-Derived Macrophage Phagocytosis Through Csf2rα-Mediated Signaling.Semantic proximity Read ↗

Regulation of Macrophage IFNγ-Stimulated Gene Expression by the Transcriptional Coregulator CITED1Semantic proximity Read ↗

Liver-Specific Deletion of Mouse CTCF Leads to Hepatic Steatosis via Augmented PPARγ Signaling.Semantic proximity Read ↗

Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation.Semantic proximity Read ↗

A Novel CCCH-Zinc Finger Protein Family Regulates Proinflammatory Activation of MacrophagesSemantic proximity Read ↗

CTCF regulates cell cycle progression of alphabeta T cells in the thymus.Semantic proximity Read ↗

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity.Semantic proximity Read ↗

Host-encoded CTCF regulates human cytomegalovirus latency via chromatin loopingSemantic proximity Read ↗

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.Semantic proximity Read ↗

Krüppel-like factor KLF10 deficiency predisposes to colitis through colonic macrophage dysregulation.Semantic proximity Read ↗

The Myc-associated zinc finger protein epigenetically controls expression of interferon-γ-stimulated genes by recruiting STAT1 to chromatinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.