Article
DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene.
Nucleic acids research - 6 Jun 2005
Oh Soon Jin, Ju Jimin, Kim Byung Chul, Ko Eunsil, Hong Bong Jin, Park Jae-Gahb, Park Joon Won, Choi Kwan Yong
Abstract excerpt
Selectivity and sensitivity in the detection of single nucleotide polymorphisms (SNPs) are among most important attributes to determine the performance of DNA microarrays. We previously reported the generation of a novel mesospaced surface prepared by applying dendron molecules on the solid surface. DNA microarrays that were fabricated on the dendron-modified surface exhibited outstanding performance for the...
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