Article
DNA microarrays with PAMAM dendritic linker systems.
Nucleic acids research - 15 Jan 2002
Benters Rüdiger, Niemeyer Christof M, Drutschmann Denja, Blohm Dietmar, Wöhrle Dieter
Abstract excerpt
The DNA microarray-based analysis of single nucleotide polymorphisms (SNPs) is important for the correlation of genetic variations and individual phenotypes, and for locating disease-causing genes. To facilitate the development of surfaces suitable for immobilization of oligonucleotides, we report here a novel method for the surface immobilization of DNA using pre-fabricated polyamidoamine (PAMAM) starburst...
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