Article
High-level expression of the Toxoplasma gondii STT3 gene is required for suppression of the yeast STT3 gene mutation.
Molecular and biochemical parasitology - 1 Sept 2005
Shams-Eldin Hosam, Blaschke Thomas, Anhlan Darisuren, Niehus Sebastian, Müller Jan, Azzouz Nahid, Schwarz Ralph T
Abstract excerpt
N-linked glycosylation is the most frequent modification of secretory proteins. The central reaction of this process in eukaryotic cells is catalyzed by the hetero-oligomeric protein complex oligosaccharyltransferase (OST). The gene STT3 gene encodes a protein, which is the most conserved among the components of the OST. In this report, we describe the isolation and functional characterization of a STT3 homologue...
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