Article
The STT3 protein is a component of the yeast oligosaccharyltransferase complex.
Molecular & general genetics : MGG - 1 Nov 1997
Spirig U, Glavas M, Bodmer D, Reiss G, Burda P, Lippuner V, te Heesen S, Aebi M
Abstract excerpt
N-linked protein glycosylation is an essential process in eukaryotic cells. In the central reaction, the oligosaccharyltransferase (OTase) catalyzes the transfer of the oligosaccharide Glc3Man9GlcNac2 from dolicholpyrophosphate onto asparagine residues of nascent polypeptide chains in the lumen of the endoplasmic reticulum. The product of the essential gene STT3 is required for OTase activity in vivo, but is not...
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