Article
STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vivo.
The EMBO journal - 16 Oct 1995
Zufferey R, Knauer R, Burda P, Stagljar I, te Heesen S, Lehle L, Aebi M
Abstract excerpt
N-linked glycosylation is a ubiquitous protein modification, and is essential for viability in eukaryotic cells. A lipid-linked core-oligosaccharide is assembled at the membrane of the endoplasmic reticulum and transferred to selected asparagine residues of nascent polypeptide chains by the oligo...
Topics
- Amino Acid Sequence
- Base Sequence
- Carbohydrate Sequence
- Conserved Sequence
- Fungal Proteins
- Genes, Fungal
- Genes, Lethal
- Genetic Complementation Test
- Glycosylation
- Hexosyltransferases
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Protein Processing, Post-Translational
- Receptors, Cell Surface