Article
DC2 and KCP2 mediate the interaction between the oligosaccharyltransferase and the ER translocon.
The Journal of cell biology - 6 Nov 2017
Shrimal Shiteshu, Cherepanova Natalia A, Gilmore Reid
Abstract excerpt
In metazoan organisms, the STT3A isoform of the oligosaccharyltransferase is localized adjacent to the protein translocation channel to catalyze co-translational N-linked glycosylation of proteins in the endoplasmic reticulum. The mechanism responsible for the interaction between the STT3A complex and the translocation channel has not been addressed. Using genetically modified human cells that are deficient in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
