Article
Identification of HLA-DQalpha and -DRbeta residues associated with susceptibility and protection to epithelial ovarian cancer.
Human immunology - 1 May 2005
Monos Dimitri S, Pappas John, Magira Eleni E, Gaughan John, Aplenc Richard, Sakkas Lazaros, Freedman Ralph, Reveille John D, Platsoucas Chris D
Abstract excerpt
Substantial evidence has been accumulated suggesting that T cells in patients with epithelial ovarian carcinoma (EOC) exhibit an antigen-driven immune response directed against the tumor cells. In the context of human leukocyte antigen (HLA), this suggests its possible involvement in the disease. Therefore, we examined the distribution of the HLA-DRB1*, -DQA1*, and -DQB1* alleles in 47 patients with EOC and 67...
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