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Article

Genetic susceptibility to breast cancer: HLA DQB03032 and HLA DRB111 may represent protective alleles.

Proceedings of the National Academy of Sciences of the United States of America - 10 Oct 2000

Chaudhuri S, Cariappa A, Tang M, Bell D, Haber D A, Isselbacher K J, Finkelstein D, Forcione D, Pillai S

Abstract excerpt

Tumors are believed to emerge only when immune surveillance fails. We wished to ascertain whether the failure to inherit putative protective alleles of HLA class II genes is linked to the development of breast cancer. We molecularly typed HLA DPB1, DQB1, DRB1, and DRB3 alleles in 176 Caucasian women diagnosed with early-onset breast cancer and in 215 ethnically matched controls. HLA DQB*03032 was identified in 7%...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 11027344
DOI: 10.1073/pnas.97.21.11451
PMCID: PMC17220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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