Article
HLA-class II haplotype associations with ovarian cancer.
International journal of cancer - 15 Dec 2006
Kübler Kirsten, Arndt Peter F, Wardelmann Eva, Krebs Dieter, Kuhn Walther, van der Ven Katrin
Abstract excerpt
The development of cancer is a multistep process that is characterized by the accumulation of genetic alterations in cells and changed cellular interactions with the surrounding healthy tissues. The human immune system is believed to be intrinsically involved in this process. The correlation of certain human leukocyte antigen (HLA)-class I and II haplotypes with tumorigenesis is documented in a variety of tumors....
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