Article
Oxidative stress and the myelodysplastic syndromes.
International journal of hematology - 1 May 2003
Farquhar Morag J, Bowen David T
Abstract excerpt
The evolution of higher organisms from anaerobic to aerobic living has promoted an elaborate mechanism of defense against potentially toxic oxidants. Many environmental toxicants implicated in the pathogenesis of myelodysplastic syndromes (MDS), including benzene and ionizing radiation, exert toxicity via pro-oxidant mechanisms. The emerging data suggest a probable genetic susceptibility to environmental...
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