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Article

Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets.

Developmental cell - 1 Jun 2005

Park Jae-Il, Kim Si Wan, Lyons Jon P, Ji Hong, Nguyen Thi T, Cho Kyucheol, Barton Michelle C, Deroo Tom, Vleminckx Kris, Moon Randall T, McCrea Pierre D

Abstract excerpt

Beta-catenin-dependent or canonical Wnt signals are fundamental in animal development and tumor progression. Using Xenopus laevis, we report that the BTB/POZ zinc finger family member Kaiso directly represses canonical Wnt gene targets (Siamois, c-Fos, Cyclin-D1, and c-Myc) in conjunction with TC...

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PMID: 15935774
DOI: 10.1016/j.devcel.2005.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15935774-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets.PMID 15935774Read ↗

Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin.Semantic proximity Read ↗

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The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development.Semantic proximity Read ↗

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