Article
Nuclear import of the BTB/POZ transcriptional regulator Kaiso.
Journal of cell science - 1 Dec 2004
Kelly Kevin F, Otchere Abena A, Graham Monica, Daniel Juliet M
Abstract excerpt
Kaiso is a BTB/POZ transcription factor that functions in vitro as a transcriptional repressor of the matrix metalloproteinase gene matrilysin and the non-canonical Wnt signaling gene Wnt-11, and as an activator of the acetylcholine-receptor-clustering gene rapsyn. Similar to other BTB/POZ proteins (e.g. Bcl-6, PLZF, HIC-1), endogenous Kaiso localizes predominantly to the nuclei of mammalian cells. To date,...
Topics
- Active Transport, Cell Nucleus
- Alanine
- Amino Acid Sequence
- Animals
- Catenins
- Cell Adhesion Molecules
- Cell Nucleus
- Glutathione Transferase
- Green Fluorescent Proteins
- HeLa Cells
- Humans
- Immunoblotting
- Immunoprecipitation
- Luciferases
