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Article

Nuclear import of the BTB/POZ transcriptional regulator Kaiso.

Journal of cell science - 1 Dec 2004

Kelly Kevin F, Otchere Abena A, Graham Monica, Daniel Juliet M

Abstract excerpt

Kaiso is a BTB/POZ transcription factor that functions in vitro as a transcriptional repressor of the matrix metalloproteinase gene matrilysin and the non-canonical Wnt signaling gene Wnt-11, and as an activator of the acetylcholine-receptor-clustering gene rapsyn. Similar to other BTB/POZ proteins (e.g. Bcl-6, PLZF, HIC-1), endogenous Kaiso localizes predominantly to the nuclei of mammalian cells. To date,...

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Identifiers

PMID: 15564377
DOI: 10.1242/jcs.01541

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