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Article

PKCdelta regulates endothelial basal barrier function through modulation of RhoA GTPase activity.

Experimental cell research - 15 Aug 2005

Harrington Elizabeth O, Shannon Christopher J, Morin Nicole, Rowlett Heather, Murphy Christopher, Lu Qing

Abstract excerpt

We have shown that PKCdelta enhanced microvascular endothelial basal barrier function, correlating with elevated RhoA GTPase activity and increased focal contact formation. In the current study, we investigated signaling pathways important in PKCdelta modulation of barrier function in unstimulate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15935342
DOI: 10.1016/j.yexcr.2005.05.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15935342-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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